The one thing needed to *achieve scientific progress* – and it is essential to make an effort at gaining this quite *simple* insight into it – is the recognition of the logical principle that negation is equally positive, or that what is self-contradictory does not resolve itself into a nullity, into abstract nothingness, but essentially only into the negation of its *particular* content; or that such a negation is not just negation, but is *the negation of the determined fact* which is resolved, and is therefore determinate negation; that in the result there is therefore contained in essence that from which the result derives – a tautology indeed, since the result would otherwise be something immediate and not a result. Because the result, the negation, is a *determinate* negation, it has a *content*. It is a new concept but one higher and richer than the preceding – richer because it negates or opposes the preceding and therefore contains it, and it contains even more than that, for it is the unity of itself and its opposite. – It is above all in this way that the system of concepts is to be to erected – and it has to come to completion in an unstoppable and pure progression that admits of nothing extraneous.
G.W.F. Hegel 1816 Science of Logic
i believe: determinate negation = entropy , content = set of instances